

Reishi
Ganoderma lucidum (Leyss. ex. Fr.) Karst.
Vademecum de Prescripción: Plantas Medicinales.
Colegio Oficial de Farmacéuticos de Bizkaia
y la Asociación Española de Médicos Naturistas.
Parte Utilizada
Los cuerpos fructíferos (carpóforos).
Principios Activos
Abundantes polisacáridos (45%): beta-D-glucana, arabinogalactanas; ganoderanas A, B y C. Triterpenos: ácidos ganodéricos A, B, C, D, F, H, K, M, R, S e Y; ganodermadiol, derivados del ácido lanostaoico. Esteroides: ganodosterona. Ácidos grasos insaturados: oleico. Prótidos: Ling Zhi-8; glicoproteínas (lectinas). Minerales: germanio, calcio.
Efectos Secundarios
Inicialmente se puede producir una descompensación en los niveles de glucosa, que se suele normalizar al cabo de unas semanas (véase apartado de precauciones).
Precaución / Intoxicaciones
Cuando se prescriba a pacientes con diabetes, el médico deberá controlar la glucemia para ajustar, si es necesario, las dosis de insulina o de los antidiabéticos orales. Cuando se prescriba a pacientes con dispepsias híper o hipo secretoras, recomendamos su administración postprandial, asociado a tisanas demulcentes (por ejemplo malvavisco, malva o manzanilla).
Bibliografía:
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Chen RY; Yu DQ. Studies on the triterpenoid constituents of the spores from Ganoderma lucidum karst. Yao Hsueh Hsueh Pao, 26:267-73, 1991.
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Chen WC; Hau DM; Wang CC; Lin IH; Lee SS. Effects of ganoderma lucidum and krestin on subset T-cell in spleen of gamma-irradiated mice. Am J Chin Med, 23:289-98, 1995
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Chen TW; Wong YK; Lee SS. In vitro cytotoxicity of Ganoderma lucidum on oral cancer cells. Chung Hua I Hsueh Tsa Chih (Taipei), 48:54-8, 1991 Jul.
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Chen WC; Hau DM; Lee SS. Effects of Ganoderma lucidum and krestin on cellular immunocompetence in gamma-ray-irradiated mice. Am J Chin Med, 23:71-80, 1995.
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Gau JP; Lin CK; Lee SS; Wang SR. The lack of antiplatelet effect of crude extracts from ganoderma lucidum on HIV-positive hemophiliacs.
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Am J Chin Med, 18:175-9, 1990.
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He Y; Li R; Chen Q; Lin Z; Xia D; Ma L. Chemical studies on immunologically active polysaccharides of Ganoderma lucidum(Leyss. ex Fr.) Karst. Chung Kuo Chung Yao Tsa Chih, 17:226-8, 256, 1992 Apr.
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Hsu HY; Lian SL; Lin CC. Radioprotective effect of Ganoderma lucidum (Leyss. ex. Fr.) Karst after X-ray irradiation in mice. Am J Chin Med, 18:61-9, 1990.
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Kawagishi H; Mitsunaga S; Yamawaki M; Ido M; Shimada A; Kinoshita T;
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Murata T; Usui T; Kimura A; Chiba S. A lectin from mycelia of the fungus Ganoderma lucidum. Phytochemistry, 44:7-10, 1997 Jan.
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Koyama K; Imaizumi T; Akiba M; Kinoshita K; Takahashi K; Suzuki A; Yano S; Horie S; Watanabe K; Naoi Y. Antinociceptive components of Ganoderma lucidum. Planta Med, 63:224-7, 1997 Jun.
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Kim RS; Kim HW; Kim BK. Suppressive effects of Ganoderma lucidum on proliferation of peripheral blood mononuclear cells. Mol Cells, 7:52-7, 1997 Feb 28.
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Lee SY; Rhee HM. Cardiovascular effects of mycelium extract of Ganoderma lucidum:inhibition of sympathetic outflow as a mechanism of its hypotensive action. Chem Pharm Bull (Tokyo), 38:1359-64, 1990 May.
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Lin CN; Tome WP; Won SJ. Novel cytotoxic principles of Formosan Ganoderma lucidum. J Nat Prod, 54:998-1002, 1991 Jul-Aug.
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Lin JM; Lin CC; Chiu HF; Yang JJ; Lee SG. Evaluation of the anti-inflammatory and liver-protective effects of anoectochilus formosanus, ganoderma lucidum and gynostemma pentaphyllum in rats. Am J Chin Med, 21:59-69, 1993.
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Lin JM; Lin CC; Chen MF; Ujiie T; Takada A. Radical scavenger and antihepatotoxic activity of Ganoderma formosanum, Ganoderma lucidum and Ganoderma neo-japonicum. J Ethnopharmacol, 47:33-41, 1995 Jun 23.
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Lieu CW; Lee SS; Wang SY. The effect of Ganoderma lucidum on induction of differentiation in leukemic U937 cells. Anticancer Res, 12:1211-5, 1992 Jul-Aug.
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Park EJ; Ko G; Kim J; Sohn DH. Antifibrotic effects of a polysaccharide extracted from Ganoderma lucidum, glycyrrhizin, and pentoxifylline in rats with cirrhosis induced by biliary obstruction. Biol Pharm Bull, 20:417-20, 1997 Apr.
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Tao J; Feng KY Experimental and clinical studies on inhibitory effect of ganoderma lucidum on platelet aggregation. J Tongji Med Univ, 10:240-3, 1990.
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Wang SY; Hsu ML; Hsu HC; Tzeng CH; Lee SS; Shiao MS; Ho CK.
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The anti-tumor effect of Ganoderma lucidum is mediated by cytokinesreleased from activated macrophages and T lymphocytes. Int J Cancer, 70:699-705, 1997 Mar 17.
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Yun TK; Kim SH; Lee YS Trial of a new medium-term model using benzo(a)pyrene induced lung tumor in newborn mice. Anticancer Res, 15:839-45, 1995 May-Jun.
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Zhang LX; Mong H; Zhou XB. Effect of Japanese Ganoderma Lucidum on production of interleukin-2 from murine splenocytes. Chung Kuo Chung Hsi I Chieh Ho Tsa Chih, 13:613-5, 582, 1993 Oct.